Wednesday, September 10, 2008

Insulin -FAQ

What is insulin?

Insulin is a hormone secreted by the beta cells of the pancreas that controls the metabolism and cellular uptake of sugars, proteins, and fats. As a drug, it is used principally to control diabetes. Insulin is not a steroid.

What type of insulin should I use for bodybuilding?
Humulin R and Humulog are the only insulins I recommend because they act fast and are out of the body fastest(this makes them the safest). I have never used Humalog but understand that aside from quicker onset and half-life it is essentially the same.

Why do I want to use insulin?
Insulin has been called "Anabolicus Maximus" by some gurus of the bodybuilding world. Insulin can give you greater gains than you have ever had using anabolics alone. Insulin, in combination with androgens and resistance exercise, may trigger maturation of satellite muscle cells (small, more or less useless cells that are held in reserve, which do not contribute to muscular strength) into mature muscle cells that do contribute to muscular size and strength. How freakin cool is that. Hyperinsulinemia has been shown to stimulate protein synthesis in isolated limb infusion experiments , these anabolic properties seem to be the result of insulin binding to IGF-1 receptors.

How much insulin should I take?
I recommend never using over 10IU. 10IU is enough to make you grow.
In general Dosages used are usually 1 IU per 20 pounds of lean bodyweight. So a 220lb bodybuilder with 9% body-fat would use 10iu of insulin(aprox200lb lean mass/20 = 10iu). But even experienced insulin users shouldn't use max dosage at the beginning of an insulin cycle. First-time users should start at a low dosage and gradually work up. For example, first begin with 2 IU and then increase the dosage by 1 IU every consecutive workout until you reach your calculated dose or determine a maximum personal dose(some people are more sensitive to insulin sides like hypoglycemia). This will allow the athlete to determine a dosage he can safely use. Insulin dosages can vary significantly among athletes and are dependent upon insulin sensitivity and the use of other drugs. Athletes using growth hormone and thyroid might have higher insulin requirements.

When do I take insulin?
It is my opinion that you should only take insulin after a work out, never before or when not working out, because before a work out you could crash and die during the workout and when your not working out it makes you fat. Some people disagree with this. IF you want, get some info from them and try it. But remember I told ya so.

when do i eat after using insulin? Immediately!!! DO NOT TRY TO TIME YOUR CONSUMPTION OF CARBS!! You should immediately take a carbohydrate AND protein drink after taking you're insulin. I've stated this twice because it is very important. Even experienced insulin users can get a surprise now and then.
Eat a meal at about an hour after using insulin. Consume another small high protein medium carb low fat meal at 2.5 hours after the injection. keep some gatoraid on hand just to make sure. Remember that insulin can still work much later so be careful and eat if you feel hypoglycemia symptoms.


what do I eat after using insulin?
Some people recommend a zero fat intake for 4 hours after taking insulin. I do not disagree with this. But if your bulking you can be a little relaxed on this. But high fat intake after taking insulin can lead to high body fat.
The carb/protein drink taken after the insulin shot should contain AT LEAST 10 grams of carbs and 5 grams of quality protein per IU of insulin injected with little or no fat(creatine taken in this drink is optional but works great). Before an hour passes you should eat a normal balanced meal(high protein low fat with carbs). At 2.5 hours after the injection you should Consume a small meal. keep some gatoraid on hand just to make sure. Remember that insulin can still work much later so be careful and eat if you feel hypoglycemia symptoms. Once again i've stated this twice because it is important.

***Some insulin users recommend far less carbs than I have stated above. This is a personal decision you will have to make since it could be very dangerous...Even deadly! My opinion is to take the carbs and learn to diet after bulking if you gain too much fat.***

How long should/can I take insulin?
Short cycles please because you could have side effects. It is suspected that you could become an insulin dependant diabetic but I have never seen proof, but is it worth the risk? I would only use it a few times a week(maximum 4 on 3 off) for no more than 3/4 weeks.

what should I avoid while using insulin?
Do not use alcohol. It lowers blood sugar, and you may experience dangerously low blood sugar levels.
Do not change your workout in the middle of a cycle of insulin. Changes in how much you exercise can change the amount of insulin you can tolerate and maintain blood sugar levels.
Do not take any recreational drugs at the same time as insulin since they could mask symptoms of hypoglycemia.
Do not change the brand of insulin or syringe that you are using without first talking to a doctor or pharmacist. Some brands of insulin and syringes are interchangeable, while others are not.
Do not use insulin if you are sick with a cold, flu, or fever. These illnesses may change your insulin requirements..
Do not use any insulin that is discolored, looks thick, has particles in it, or looks different from the way it looked when you bought it.
Do not use OTC drugs that will cause drowsiness within 6 hours of using insulin.
Do not go to sleep within 4/6 hours of using insulin since you can develop hypoglycemia while asleep and not have warning signs.

what are the possible side effects of insulin besides hypoglycemia?
Rarely, people have allergic reactions to insulin. Seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Hypothetically, one could become an insulin dependent diabetic if insulin is used too long.

IGF + Insulin
If you plan on doing IGF1 with Insulin, listen closely IGF1 is not that expensive, sure you can get away with using less by including insulin in the stack, but IGF1 and Insulin together have a pro-insulin effect on your blood sugar balance. It can enhance the chances of a hypoglycemic episode ten fold. I would recommend against it for any one not ABSOLUTLY comfortable with insulin or IGF1.

Here is how insulin and IGF1 work together. Igfbp3 is the binding protein, which allows IGF1 to remain active in the system for a long enough period of time to really work its magic. IGF1 by nature has a half-life of less than 10 minutes by its self. The molecule was so small it would escape the blood stream very rapidly. This was the reason IGF1 was so "underground". It took very frequent injections at high dosages to achieve even minimal results. Aside from this reconstituting the compound required a degree in biochemistry. This short acting version was the only IGF1 known until recently IGF1 would have been administered in 100 mcg dosages 4-6 times a day. That is a hell of a lot of IGF1. That explains a lot of the distended bellies. Now with R3 long chain IGF1 and the Binding protein IGFBP3 IGF1 will last up to 6 hours in the system. By binding IGF to the IGFBP3 you make the molecule larger and it gets trapped in the blood stream until the protein is broken down and the IGF molecule escapes. You can further its life by combining Insulin with it, although I here its very risky. Insulin prevents the breakdown of IGFBP3 and leaves the IGF1 molecule roaming free in the blood stream for longer periods of time up to 12 hours as insulin levels return to normal IGFBP3 will begin to break down and the IGF1 will escape from its bound protein IGFBP3 again having a half life of less than 10 minutes.

Insulin should be taken at the normal dosage it is usually administered at minus 10% about 45 minutes prior to the IGF1 infusion. Again let me remind you this can be deadly if you don't know what you are doing. And of course do not use Insulin for the nighttime injection of IGF1 by taking it in the morning you prolong the IGF1's half life to 12 hours and then take a 6 hour injection, you should be fine. Hell if you want to eat a big bowl of rice and drink another 100g of simple carbs 45 minutes before the bed time IGF1 infusion you could spike insulin for at least a few hours of extended IGF1 activity. If your not going to be using insulin in the stack then go ahead and do the same in the morning.

1 comment:

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